The Faculty of Biomedical Engineering actively develops scientific partnerships, takes part in scientific projects and performs scientific topics financed from the state budget of Ukraine, at the request of enterprises and organizations of Ukraine, as well as at the request of companies from other countries.
Development of the concept of a multifunctional prosthetic rehabilitation center with an innovative and educational component for patients with limb amputation
The development of a functioning prototype of a multifunctional prosthetic rehabilitation center for providing medical services to patients with limb amputation with innovative and educational and inclusive components and its organizational testing took place within the framework of the project 2023.04/0073 with grant support from the National Research Foundation of Ukraine “Development of the concept of a multifunctional prosthetic rehabilitation center with an innovative and educational component for patients with limb amputation” (2024-25).
Principle investigator: Dr. of Medical Sciences, Prof. Igor Khudetsky.
The relevance of the project is due to the increase in the number of patients with limb amputations as a result of the war and the need to provide comprehensive prosthetic rehabilitation care and their further social adaptation.
The scientific and methodological prerequisites for creating a prototype of a multifunctional prosthetic and rehabilitation center (PMPRC) were the development of the “Concept of a multi-level system of prosthetic and rehabilitation care for patients with limb loss”, and the “Concept of a multifunctional prosthetic and rehabilitation center with an innovative and educational component for patients with limb amputation”, a program of advanced training and postgraduate training for specialists in prosthetics, orthotics and physical therapy for patients with amputees, as well as a master’s educational program in the specialty “Therapy and Rehabilitation” (occupational therapy).
Practical implementation and implementation. The creation of the PMPRC and its integral component, the educational and scientific laboratory of prosthetics, medical rehabilitation and occupational therapy became the basis for further practical implementation of the project.
A master’s degree program in the specialty “Technologies of Medical Diagnostics and Treatment” (prosthetics-orthotics) was developed, a certificate program “Medical Engineering Technologies in Prosthetics” within the framework of the educational program program “Medical Engineering” under which recruitment and training of veterans, including those with amputees, is carried out.
Laboratory equipment, which was purchased within the framework of the project and with the funds of sponsors, is actively used in the educational process, practical training and scientific research.
The scientific value of the project lies in creating an example of a new type of multifunctional prosthetic and rehabilitation centers – the highest level of prosthetic and rehabilitation care, integrating medical, engineering and technological, scientific and research and educational activities. They provide comprehensive medical care, testing of innovative solutions, conducting research, training specialists and implementing an individualized approach to the patient, taking into account his medical, psychological, social and professional needs. An innovative approach to the integration of educational and rehabilitation components in a multifunctional prosthetic and rehabilitation center will allow to improve the quality of prosthetics, ensure sustainable development of rehabilitation infrastructure and prepare highly qualified specialists to work in the conditions of modern challenges.
Social aspect. The implementation of the project in terms of education for veterans is a practical example of socialization of patients with limb amputations and other combat injuries.
No. 0123U100866
Implementation period: 2023-2028.
Title: Methods and models of object state identification in medical decision-making tasks.
Purpose: the purpose of the project is to promote new approaches based on machine learning to assess the condition of objects and provide support in medical decision-making.
Within the framework of this project, joint work is currently underway with the Laboratory of Biometric Technologies of the University of Calgary on the creation of a stress monitoring system based on physiological indicators collected by wearable devices (such as smart bracelets).
Potential scope of application: broad sections of the population, athletes, emergency responders, military personnel, etc.
Supervisor: Evgeny Nastenko, Doctor of Science, Candidate of Technical Sciences, Professor
Department of Biomedical Cybernetics.
No. 0117U002933 (initiative)
Implementation period: 2022-06.2027 (continuation of topic 0117U002938)
Title: Development of physical therapy technologies and technical means of their implementation.
Purpose: To develop modern effective technologies for the restoration of the musculoskeletal system of a person using both known and new technical means.
Supervisor: Ihor Khudetskyi, professor, MD.
Department of biosafety and human health.
No. 0122U200933 (1,565,500.00 UAH)
Funding: State Budget (MES)
Implementation period: 09.2022-12.2023
Title: Development of methods of increasing the biological activity of food products for special medical purposes.
Purpose: Development of technologies for obtaining food products for special medical purposes with immunomodulatory, cardio- and gastroprotective properties using methods of increasing the biological and nutritional value of raw materials of biological (biotechnological) origin.
Supervisor: Aleksander Galkin, Doctor of Science, Professor.
Department of translational medical bioengineering.
Сontract No. 466/2020T dated November 11, 2020 (farm contract) with the State University “Scientific and Practical Medical Center of Children’s Cardiology and Cardiac Surgery of the Ministry of Health of Ukraine” (217,000 hryvnias)
Deadline: 2020.
Title: Development of a hardware and software complex for the design and testing of aortic biological heart valve prostheses.
Principal investigator: Shlykov Vladyslav, Ph.D., associate professor.
Department of Biomedical Engineering
No. 0120U105183 (1,981,118.00 UAH)
Implementation period: 2020-2021.
Title: Development of the concept of specialist training and professional development in biosafety and biosecurity.
Results: The concept of training specialists in biosafety and biodefense was developed, namely: the educational program “Biosafety and biodefense” specialty 163 – Biomedical engineering for students of the second (master’s) level of higher education. • The concept of improving the qualifications of employees of enterprises (institutions) of various industries and military personnel in matters of biosafety and biosecurity management at various levels (local, regional, national) has been developed (including the educational plan). • Educational and methodological support for the training and retraining of biosafety and biosecurity specialists has been developed (textbooks and training manuals on the discipline, which are elements of the relevant educational program). • The concept and regulations on educational-practical and educational-scientific laboratories with: modeling of biothreats and biosafety management were developed; identification of biohazards. Supplying the labor market and specialized institutions and organizations with modern qualified biosafety and biosecurity specialists will allow for domestic high-tech development of methods and means of combating biothreats, management and biosafety at various levels (local, regional and national) – for the needs of national security, the state economy, effective and safe functioning of institutions, enterprises and organizations, as well as ensuring the health of citizens and the normal functioning of the natural environment.
Principal investigator: Ihor Khudetskyi, professor, MD.
Department of Biosafety and Human Health and Department of Translational Medical Bioengineering.
No. 0120U105251 (4,069,775.00 UAH)
Grant of the National Research Fund of Ukraine 2020.01/0226
Deadline: October 2020-2021.
Title: Experimental study of the effectiveness and safety of the use of new phytochemical and bacterial drugs for the treatment of coronavirus and other common infections.
Purpose: The pharmacotherapeutic and phytochemical design of a complex herbal preparation with expected antiviral activity was carried out: promising medicinal plants containing flavonoids and a favorable raw material base in Ukraine were identified (Apium graveolens, Arctium lappa, Calendula officinalis, Filipendula vulgaris, Galium verum, Humulus lupulus, Linaria vulgaris , Petroselinum crispum, Sophora japonica). The identification and research of the content of biologically active substances in selected medicinal plant raw materials, primarily flavonoids, was carried out. The phytochemical and pharmacotherapeutic design of preparations based on various medicinal plant raw materials, which are promising for medicine, was carried out prevention of coronavirus and other widespread human infections. A laboratory technology for obtaining a complex phytopreparation, methods of its quality control were developed, and experimental series of the drug based on medicinal plant raw materials were obtained.
Principal investigator: Zadorozhnya Viktoriya, member-cor. NAMNU, Doctor of Medicine, Professor.
KPI is a co-executor of the grant. It is carried out at the Department of Translational Medical Bioengineering, the head is Lutsenko Tetyana Mykolaivna, Ph.D., associate professor.
No. 0119U103789 (initiative)
Implementation period: 01.01.2020 – 12.2024
Title: Development of innovative biomedical technologies and products for diagnosis and treatment of human pathologies.
Purpose: To carry out a scientific substantiation of technologies for obtaining highly informative means for immunoenzymatic diagnostics and immunobiological drugs for therapeutic purposes.
Principal investigator: Aleksander Galkin, Doctor of Science, Professor, responsible executor T.M. Lutsenko, Ph.D.
Department of translational medical bioengineering.
Without dr/r (initiative)
Implementation period: 2019-2022 (continued)
Title: Tools for controlled hypothermia of patients with cardiovascular pathology.
Principal investigator: Maksimenko Vitaly, Doctor of Medicine, Professor.
Department of Biomedical Engineering.
No. 0223U000145 (initiative)
Implementation period: 2017-10.11.2022.
Title: “Methods and models of identification of states of biological objects”.
Results: New approaches have been developed to solve the actual problems of automated diagnostics in the class of medical problems “norma-pathology”, differentiation of relatives by clinical manifestations of diseases, problems of assessing the patient’s condition. The developed projects are based on research and new results in the field of texture analysis, algorithms for the construction of classifiers in the Random Forest class, modeling of hybrid classifiers based on convolutional networks and self-organized forests, class-oriented selection technologies in classification tasks with an excessively large number of features. The obtained results made it possible to effectively solve the task of automated diagnosis based on ultrasound images of the normal-pathological state in diffuse liver diseases and coronary heart disease, diagnosis and classification of the types of lesions (ground glass, cobblestone, consolidation) of the lungs based on CT images in the case of Covid-19, differentiation on CT images of the lungs of chemoresistant and chemosensitive forms of tuberculosis.
Principal investigator: Evgeny Nastenko, Doctor of Science, Candidate of Technical Sciences, Professor.
Department of Biomedical Cybernetics.
No. 0117U002938 (initiative)
Implementation period: 07.2017-06.2022.
Title: Development of physical therapy technologies and technical means of their implementation.
Purpose: development of new technologies of physical therapy and technical means of their implementation for the restoration of the human musculoskeletal system.
Principal investigator: Ihor Khudetskyi, Doctor of Medicine, Professor.
Department of biosafety and human health.
No. 0117U006954 (initiative)
Implementation period: 2017-2022.
Title: Information technologies for assessment and correction of the state of health of university students.
Main results: An original software product designed to determine the functional state of the circulatory system by comparing the test results with the dosed load according to predetermined functional states of the blood circulation was developed. The use of this product allows users to choose the type of motor activity, the volume and intensity of physical exertion depending on the functional type of the body’s reactions.
Principal investigator: Boyko Hanna, Ph.D., associate professor.
Department of health and sports technologies.
Without dr/r (initiative)
Implementation period: 2014-2019.
Title: Tools for controlled hypothermia of patients with cardiovascular pathology.
Purpose: Development of a set of disposable hypothermia vest consumables as part of the patient’s warming/cooling system, which allows to increase the viability of heart and brain tissues in acute myocardial infarctions and circulatory disorders.
The result of the work is the development of documentation for the production of a tool for controlled hypothermia of patients with cardiovascular pathology.
Principal investigator: Maksimenko Vitaly, Doctor of Medicine, Professor.
Department of Biomedical Engineering.